Vitamin D PPT: Structure, Sources, Consequences: Vitamin D belongs to the class of fat-soluble secosteroids that increases intestine calcium, magnesium, and phosphate absorption, among other things. Vitamin D3 (also known as cholecalciferol) and vitamin D2 are the two most significant molecules in this category in humans (ergocalciferol).
Vitamin D PPT: Structure, Sources, Consequences
Calcitriol, the biologically active form of vitamin D, circulates in the blood as a hormone, playing a key role in calcium and phosphate regulation, as well as bone formation and remodelling. Calcitriol has a variety of different impacts, including some that affect cell growth, neuromuscular and immunological function, and inflammation reduction.
Vitamin D tablets are frequently used to treat and prevent vitamin D deficient diseases like osteomalacia and rickets.
Vitamin D is also utilized to cure bones that are weak or fragile. Vitamin D is also used to treat brittle bones, heart disease, asthma, hay fever, and a variety of other ailments.
Vitamin D Sources:
Fish, eggs, and fortified milk all contain vitamin D.
When exposed to sunlight, it is also produced in the skin. Vitamin D is stored in fat during periods of sunlight and subsequently released when sunlight is not available.
Consequences of Vitamin D:
Hypercalcemia, a significant indicator of vitamin D toxicity, is caused by a vitamin D overdose and is manifested by increased urine and thirst. If untreated, the hypercalcemia causes calcium deposits in soft tissues and organs such as the kidneys, liver, and heart, causing pain and organ damage.
Hypercalcemia, which includes anorexia, nausea, and vomiting, is the most common symptom of vitamin D overdose. Polyuria, polydipsia, weakness, sleeplessness, nervousness, pruritus, and eventually kidney failure may occur. Proteinuria, urinary casts, azotemia, and metastatic calcification (especially in the kidneys) are also possible side effects. Other indications of vitamin D poisoning include mental retardation in young children, aberrant bone growth and formation, diarrhea, irritability, weight loss, and severe depression.